No abstract

A novel target compounds (9a-j) were design and synthesized and characterized by 1H & 13C NMR, ESI-MS spectral analysis. Further, these were tested for their anticancer activity against three human cancer cell lines such as MCF-7, MDA MB-231 (breast), A549 (Lung) and adriamycin was used as positive control. Among ten compounds, two compounds like 9b and 9j were showed a significant anticancer activity compared to control drug.

A mild and operationally simple method is presented for the cyclization reactions of 2‐aminoacetophenones or enamines with phenylalkynes to form indoles and pyrroles, respectively.