Asthma attack was one of the disease having symptoms of nearly the same each other. So that it can be grouped into some of symptoms by sub this shows a tendency to each. This is in accordance with the application of a method of WP and TOPSIS that is used in diagnose an asthma attack. Not widely used method of WP or TOPSIS in diagnose asthma attack because Commonly used in the support system decision so as to give diagnose that is less valid. In this research, the WP-TOPSIS method was combined by utilizing the advantages of each method in providing output and fix by computation from a method of WP-TOPSIS with a disregard a couple of things as the value of the cost of which is not possessed expert system. So it expected to results from output better. By using 40 data of experiment to the 2 people experts obtained the results of the level of accuracy of the average namely WP 21,25%, TOPSIS 21,25% and combined WP-TOPSIS 65%. Obtained increase in extent accuracy namely 43,75 %, Thus methods combined better than WP and TOPSIS in its use in expert system diagnose asthma attack.