How to cite this article: P. Lakshmi Prashanthi, Rajoo Ramachandran, Adhilakshmi, Prabhu Radhan, Venkata Sai. Standardization of PSOAS muscle index measurements using computed tomography. International Journal of Contemporary Medicine Surgery and Radiology. 2020;5(1):A169-A172. Psoas muscle index (PMI). Results: It was observed that mean psoas muscle index decreased significantly with increasing age. It was also observed that mean psoas muscle index in female population was comparatively less than mean psoas muscle index in male population. Conclusions: Standardization of mean psoas muscle index enables evaluating normal and abnormal mean psoas muscle index thereby, predicting potential sarcopenia and initiate appropriate patient management / intervention. This can be used for predicting morbidity and mortality in cirrhosis, lung cancer, colorectal cancer patients.