Vancomycin is a potent tricyclic glycopeptide antibiotic, used to treat bacterial infections caused by Gram-positive bacteria. It is renally excreted. Therefore, monitoring trough levels is highly important to ensure safety and efficacy. Vancomycin has good stability after preparation, which lasts for weeks, depending on temperature. Hence, pharmacy, in KAMC-MNGHA, used to provide each patient with all doses to cover 24 hours. Unfortunately, because doses and/or frequency are usually increased/decreased for the patients based on their renal function and drug levels, many doses are not given and wasted. That practice has been changed to prepare each dose of vancomycin 2 -3 hours before time of administration. As a result, number of wasted doses has decreased significantly.Consequently, hospital resources are saved and shortage of essential materials is prevented.