In this study, new tetrazole [A1-A5] were prepared by the reaction of Schiff base with sodium azide in tetrahydrofuran (THF) by the traditional method (reflux) and microwave technology. The prepared compounds were characterized by physical properties, UV-Vis, FT-IR, 1H-NMR, 13C-NMR spectral, and C.H.N analysis. TLC checked the purity of these compounds. Antibacterial behaviors were investigated against a variety of bacteria, including Escherichia coli, and Klebsiella pneumonia Gram (-) ve, Staphylococcus aureus, and Staphylococcus epidermidis Gram (+) ve. The laser efficacy of the [A1-A5] was evaluated after they were radiated by laser for (10, 20, 30) seconds. As the melting point, and color of the substances were determined, it was discovered that they were unaffected, and did not disintegrate or polymerize. Using the Chem3D 19.0 program, the heat of the formulation of the [A1-A5] was investigated.

No abstract

No abstract

The aim of this work describes the synthesis of disperse dyes in the derivative of 2-amino -4-hydroxy thiazole, which can be used as dyes for polyester fabrics with orange and red color They were obtained by preparing, (2-amino-4hydroxy-thiazole), then the latter compound was diazotization and couplings to produced (compound III and IV), Which were introduced by another coupling with diazonium salt of compound I diazotization to synthesize disperse (VII,VIII). The synthesized heterocyclic and synthesized dyes were studied by UV Spectroscopy, FT-IR, 1 H-NMR and 13 C-NMR. The substituted dyes Penetrate with good depth on polyester fabrics with a shade of orange and red colors, respectively. That increase heteroatoms and the conjugation in the dyes structure lead to high redshifts and the brightness of shades, color stability is high and fastness properties. The antibacterial activities were studied against different kinds of bacteria, namely Eschershia coli and Klebsiella Pneumonia Gram (-) ve, Staphylococcus aureus and Staphylococcus epidermidis Gram (+) ve. In addition, evaluation of laser efficacy was showed for the compounds (I,III,IV,VII,VIII) were radiated by laser for (10, 20, 30) seconds, It was observed that the prepared compounds were not affected and did not polymerize or degradation when measuring melting point and color.

"Preparation of heterocyclic compounds with new pharmacological properties. Preparation of organic compounds with high biological activity against bacterial germs. Diagnosis of prepared compounds by physical and spectroscopic methods. Spectroscopic and physical measurements validated the prepared compounds. Studying the effect of lasers on these compounds, as it has been proven that the rays do not affect them.