Background And Aims: Hypotension is commonly associated side effect with Subarachnoid block (SAB) and it is widely used technique for parturients undergoing lower segment caesarean section (LSCS). Hypotension is detrimental to both mother and baby so prophylactic measures are essential to prevent it. So this study was conducted to use perfusion index as a predictive non-invasive measure of hypotension in parturients posted for LSCS under SAB. Materials And Methods: After obtaining written and informed consent, this prospective, double blind, observational study was carried out in 100 term pregnant females aged 20-40 years and were devided in two groups (50 in each) based on baseline PI, PI values ≤3.5 were in Group I and PI values >3.5 in Group II. All parturients were given inj. bupivacaine 0.5% Heavy 2 ml (10 mg) in SAB. Incidence of hypotension and other parameters, requirement of rescue drug and uids were recorded. Results: In Group I (PI≤3.5) incidence of hypotension (8 vs 40, P=0.00), requirement of rescue drug (mephentermine) per parturient (1.92±4.92 vs 8.4±5.6, P=0.00) and Fluid requirement (ml) per parturient (1243.20±115.24 vs 1381.60±110.79, P=0.00) were signicantly less as compared to Group II (PI>3.5). (p<0.05) Conclusion: Parturients with PI>3.5 are at higher risk of developing hypotension after subarachnoid block and requirement of vasopressors and uid is more as compared to those parturients with PI≤3.5.

Objective: This study was designed to evaluate the efcacy of two prophylactic infusion dose of phenylephrine (50 and 75 μg) along with oxytocin to prevent oxytocin induced hypotension in parturients undergoing caesarean section. With institutional Ethical committeeMaterial and Method: (IEC) clearance and informed written consent, 420 term parturients undergoing elective caesarean section under SAB were randomly allocated to 3 groups of 140 each. Group C (3 IU oxytocin with normal saline) Group PE50 (3 IU oxytocin with phenylephrine 50μg) Group PE75 (3 IU oxytocin with phenylephrine 75μg) diluted to 10ml with normal saline and infused over 5 min after baby delivery. No of episode, incidence, duration of hypotension, rescue vasopressors requirement and any adverse effect observed. In present study, total 67(47.85%), 50 (35.71%) and 26Results: (18.57%) patients developed hypotension (P= 0.000) and total 110, 65 and 31 episodes (1.64±0.79, 1.30±0.54, 1.19±0.40 per patient) (P= 0.000) in group C, PE50 and PE75 respectively, total duration of hypotensive episode were 349, 217and 107 mins in three groups, and it consumed 131,75, 35 doses (50 μg each) of phenylephrine (1.95±1.13, 1.50±0.81,1.34± 0.48 dose Per patient) (P= 0.005) and total 97.76±56.69μg, 75 ±40.72 μg , 67.30 ±24.25 μg (p= 0.003) phenylephrine per patient as rescue vasopressors in group C, PE50 and PE75 respectively. TheConclusion: prophylactic co-administration of 75μg phenylephrine with oxytocin effectively reduced the incidence of oxytocin induced hypotension in term parturients undergoing caesarean section under subarachnoid block compared to 50μg phenylephrine.