We reviewed echocardiograms of 31 fetuses with isolated GSC. None of the fetuses had structural heart defects consistent with congenital heart disease. There were no functional abnormalities. There was no statistical difference between the GSC group and normal fetuses by measurement of our FECHO parameters. In five (16%) fetuses, we identified left axis shift of 45 to 75 degrees off the sternum to spine axis within the left chest. Conclusions: Structural and functional cardiac abnormalities are rare in fetuses with isolated GSC. The axis shift of the heart within the thorax is likely associated with amount of bowel that is outside the abdomen. This axis shift is also seen with omphalocele where the larger the omphalocele the greater the shift.

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