The mechanism of obesity is a complex one, while in regulating feeding behavior there are other factors that act, among which the hypothalamic centers, the metabolic balance of the internal environment, information's digestive system, endocrine system or adipose tissue response. The study on a group of cats aimed to evaluate specific biochemical parameters of lipid metabolism -cholesterol, triglicerides, LDL, HDL, including a parameter less assessed in medical veterinary practice -apolipoprotein B (Apo-B). Increased levels of this parameter are found in disorders such as obesity, hiperlipoproteinemia, nephrotic syndrome, diabetes etc. The results revealed significant disorders of lipid metabolism with predisposition to obesity, hyperlipidemia and cardiovascular disease.