Oroxylum indicum has long been used in Asian traditional medicine to prevent and treat respiratory diseases, diabetes, diarrhea and other conditions. Oroxylin A is a flavone that is present in Oroxylum indicum and in Scutellaria baicalensis. Because the root extracts of both plants have been shown to have anti-allergic effects, the authors investigated whether oroxylin A is likely to have beneficial effects on allergic asthma using female Balb/c mice and rat RBL-2H3 mast cells. Antigen-induced degranulation was measured in vitro by measuring β-hexosaminidase activity. A murine ovalbumin-induced allergic asthma model was used to test the in vivo efficacy of oroxylin A. Sensitization and challenge of ovalbumin induced allergic asthma responses, the accumulations of eosinophils and Th2 cytokine levels in bronchoalveolar lavage fluid and lung tissues. Oroxylin A administration decreased numbers of inflammatory cells, especially eosinophils, and reduced the expression and secretion of Th2 cytokines, including IL-4 and IL-13, in lung tissues and bronchoalveolar lavage fluid. Histologic studies showed oroxylin A reduced inflammatory signs and mucin production in lungs. These findings provide evidence that oroxylin A has potential use as an anti-allergic therapeutic.
This study to suggest a plan to utilize new sports band wrestling derived from wrestling events into school physical education. The research method was based on literature research on wrestling in-depth interviews were conducted with a group focused as a qualitative research method by as well as consisted of a total of 11 experts, 2 advisors from band wrestling developers, 3 wrestling majors, 3 sports-related majors, and 3 physical education professors, as participants in the study A qualitative study was conducted through in-depth interviews as a group-focused research method. About the utilization method of band wrestling in the school physical education, which is the purpose of this study First, In terms of the value of band wrestling as a new sports the exercise effects, game rules, participants and safety aspects were examined. Second, As a the utilization method of using band wrestling in school physical education the aspects of character education, location, intrigueresting, school violence prevention were investigated. Based on this, I would like to present basic data on how to use band wrestling in school physical education.
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