The question whether an implant could be placed in an infected site has often been raised and addressed in the literature by several authors. There are several studies that have successfully placed implants in infected sites [1][2][3][4][5][6]; however, all these studies removed granulation tissue before placing the implant as a part of their clinical protocol [7][8][9][10][11][12][13][14][15][16]. In this study, the implants were placed in infected sites without curettage.A prospective clinical study was done with a total of 10 cases. The selected infected, maxillary anterior teeth presented with either chronic or acute periapical lesions with poor to a hopeless prognosis. A standardized surgical and prosthetic protocol was developed. Implants were placed and cases were evaluated at six-month follow-up. Using pre-and postoperative cone beam computed tomography (CBCT), data were collected [16][17][18][19][20][21][22]. The result reflects and confirms the hypothesis that endosteal implants can be successfully integrated in infected sites. However, alveolar ridge resorption after the tooth extraction is a frequent occurrence and may significantly reduce the residual bone volume [23][24][25][26][27][28]. This study is a proof of principle that sockets can heal naturally with immediately placed implants in infected sites and tissue shrinkage can be reduced by utilizing least invasive surgical and prosthetic protocol.