Background: Corona infection is a viral infection that attacks the respiratory system. Patients who are classified as suspect Covid-19 undergo independent isolation at home or in the hospital so that they do not transmit to other people and their health conditions are monitored. Home care of patients with suspected Covid-19 with comorbids such as COPD must be carried out carefully by looking at indicators of respiratory function, such as cough frequency and sputum (number, color). This is because respiratory problems in Covid-19 patients indicate damage to the condition and can lead to death. Method: The study design was a case report. The purpose of making this case report is to describe the home care process for suspected Covid-19 patients with comorbid COPD. Case description: A female client, 50 years old, has a Covid-19 infection, namely, dry cough, runny nose, lost smell, diarrhea with PCR + test, who has a COPD comorbid with thick, cloudy sputum and is difficult to remove and undergoes isolation at home. Treatment emphasizes increasing immunity through nutritional support, herbs, rest, antibiotics / symptom medications and stress management. The client shows an improvement in health status after undergoing 7 days of home treatment. Conclusion: Treatment of the client suspect Covid-19 with comorbid COPD can be done at home with quick results