Introduction Interstitial lung diseases are the major cause of mortality in connective tissue diseases.Objectives Our aim is to describe patients with interstitial lung disease associated with connective tissue diseases (CTD-ILD) in the Chest Clinic, Colombo 08.
MethodsWe conducted a descriptive cross-sectional study at the Central Chest Clinic, Colombo, Sri Lanka and data of all patients attending the Clinic were analysed.
ResultsThe sample consisted of 83 consecutive patients diagnosed with CTD-ILD. The age ranged from 24 to 72 years with mean (SD) age of 55.6 (10.6) years. The majority was female patients (n=70, 88.6%). The majority 53.0% (n=44) had RA and SSc was the second commonest CTD-ILD (n=22, 26.5%). NSIP 51(61.9%) was the most frequently observed HRCT pattern in our cohort whereas UIP was the second commonest.RA-ILD subgroup demonstrated female (n=37, 86.0%) preponderance. NSIP (n=24, 55.8%) was the commonly observed HRCT pattern followed by UIP (n=15, 34.9%) pattern. Among RA-ILD patients, 28 (65.1%) had positive Rheumatoid factor. Majority of (n=20, 90.9%) SSc-ILD were females. Sixteen (72.7%) of them had NSIP pattern in HRCT analysis followed by UIP (n=6, 27.3%).Conclusion RA-ILD was the most frequent type of CTD-ILD followed by SSc. More importantly; the present study revealed the predominant NSIP pattern and clear female preponderance in RA-ILD compared to global data. We recommend prospective multicenter studies to be carried out and prospective disease registries to be established to explore the epidemiological, clinical, radiological and prognostic characteristics of CTD-ILD in Sri Lanka.
Background: treatment. Objective: with clinical presentation, diagnostic modalities and treatment outcome Method: An audit was carried out revising clinical records of patients treated for peripheral lymph node enlargement due to tuberculosis at the Central Chest Clinic, Colombo. Results: were the cervical lymph nodes (94%). Mantoux test positivity (>10mm) primary investigations was seen in 122 (97%) of patients. Out of all supportive primary and ancillary diagnostic tests. Paradoxical reactions reactions and drug induced hepatitis were noted in 17%. Eighty-two patients achieved complete clinical resolution at the end of 6 months while others were found to have residual lymph nodes necessitating further evaluation. Conclusions: treated based on primary and ancillary diagnostic test results. Prospective studies are recommended for more descriptive assessment. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Genitourinary tuberculosis is a challenging clinical entity which can affect the entire male genital tract. Seventy-five- year old male presented with a testicular lump masquerading a testicular malignancy. Histological and microbiological examination of testicular biopsy specimens established the diagnosis of tuberculosis. Isolated testicular tuberculosis is rarely reported. High degree of clinical suspicion and histological sampling are paramount important in the process of diagnostic evaluation.
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