Background: Hip arthroplasty (HA) is the surgical replacement of all or part of the hip joint with an artificial device. Essentially, the discharge planning nurse plays crucial role to ensure that all instructions are included to enhance patients outcome. Aim: Assess the relation between discharge instructions compliance and quality of life for the patients post hip arthroplasty Design: A descriptive exploratory research design was utilized for the conduction of this study. Setting: The study was conducted in outpatient's orthopedic clinic at El Hadara hospital affiliated to Alexandria University Hospitals. Study subjects: A purposive sample of (50) adult patients post hip arthroplasty. Data Collection Tools: I -Patients interviewing questionnaire, II -Patients Compliance assessment sheet. III-Patient's quality of life short form (SF-36) questionnaire. Result: (48%) of patients were compliant, (52%) of them were non-complaint as well as (36%) of patients had low QoL, (46%) had average QoL; & (18%) had high QoL. Conclusion: Less than half of studied patients were compliant while slightly more than half of them were non-complaint. Along with slightly more than one third of the patients had low QoL, less than one quarter of them had high QoL & slightly less than half of them had average QoL; Additionally, there were highly statistically significant positive correlation between total level of compliance among the studied patients post hip arthroplasty surgery according & total quality of life level. Recommendations: The necessity of designing, implementing and evaluation of collaborative, informative, attractive discharge plan that address arthroplasty discharge needs, considering the health care providers time constraint and patient's short hospital stay.