Guillain-Barre syndrome is a post infectious ascending, usually demyelinationg polyradiculoneuropathy. Dengue fever as an antecedent infection in GBS is uncommon. A 39-year-old female presented with acute flaccid weakness of both upper and lower limbs which developed in ascending and progressive fashion following a febrile illness of three days. During work-up IgM for dengue virus was found positive. Diagnosis of Guillain-Barre syndrome was made based on neurologic manifestations, the typical CSF findings and pattern of electrophysiological study and exclusion of other pathologies. Patient was treated with intravenous immunoglobulins. During the course of illness, she developed lower motor neuron type trigeminal, facial, glossopharyngeal, vagus and hypoglossal nerve palsy and autonomic involvement. She had significant recovery and was able to talk, eat and walk six weeks later. Dengue is endemic in Bangladesh. Post dengue Guillain- Barre syndrome in adult, as shown in previous reports, should now be considered in the part of spectrum of neurological complications of this infection. DOI: http://dx.doi.org/10.3329/jom.v13i2.12772 J Medicine 2012; 13 : 246-249
Diabetes Mellitus is one of the leading non-communicable diseases all over the world including Bangladesh. Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, lipid and protein metabolism. Impaired lipid profile is commonly present in type 2 diabetes. We aimed to research serum lipid profile abnormalities hypothesizing that early detection and treatment of lipid abnormalitiescan minimize the risk for atherogenic cardiovascular disorder and cerebrovascular accident in patients with type 2 diabetes mellitus. This observational cross sectional study was carried out in the department of Biochemistry, Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM).A total 105patients with T2DM of age within the range of 30-45 years were selected& their Fasting blood glucose (FBG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG) and glycatedhaemoglobin (HbA1c) levels were evaluated. Significantly higher mean serum levels of TC, TG and LDL and significantly lower mean serum levels of HDL were noted in patients with diabetes . Significant correlations were observed between HbA1c value and serum levels of TC, TG and HDL (p<0.05) but no correlation of HbA1c value withlow density lipoprotein in diabetes patient.The study showed widespread lipid abnormalities in the course of diabetes triggered dyslipidemia as hypercholesterolemia, hypertriglyceridemia, elevated LDL and decreased HDL.
Bangladesh Crit Care J March 2019; 7(1): 44-47
We report a 25-year-old man presenting with fever and weight loss for the six months along with anemia, hepatosplenomegaly and axillary lymphadenopathy. Laboratory investigations showed pancytopenia. Bone marrow and splenic aspiration was inconclusive, lymph node biopsy revealed LD bodies thus confirming visceral leishmaniasis. The case high lights the need of accepting lymph nodes as a site for diagnosing kala-azar and kala-azar lymphadenopathy is not as elusive as we think. Â Â DOI = 10.3329/jom.v9i2.1441 J MEDICINE 2008; 9 : 108-109
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