Objective: To determine the clinical presentation and histopathological evaluation of patients undergoing thyroidectomies at tertiary care Hospital. Methodology: This cross-sectional study was done at department of general surgery of LUMHS/Jamshoro. Duration of the study was 1 year from October 2017 to September 2018. All the cases with a diagnosis of thyroid disorder and underwent thyroidectomy were selected and above 25 years of the age were included. All the surgeries were carried out by senior surgeons along with the cooperation of the ENT surgeons. After surgeries specimens of all the cases were sent to the diagnostic laboratory for the histological assessment. Data was collected via self-made proforma. Results: Of 58 patients majority i.e. 43.10% were found with age group of 35-44 years. Females found in the majority 63.80%. The swelling was noted among all of the cases, followed by pain, difficulty in swallowing, difficulty in breathing and others 8.62%, 10.34%, 20.68% and 25.68% respectively. Adenomatous goiter was the most common histopathological finding in 82.75% cases, papillary carcinoma was found 8.62%, follicular carcinoma was only in one case and anaplastic carcinoma was also in 1 case. Conclusion: Swelling, difficulty in swallowing and difficulty in breathing were the most common clinical features. Adenomatous goiter was the most common histological finding and papillary carcinoma was the commonest malignancy.

Objectives: To evaluate pattern and presentation of pyogenic granuloma in pregnant patients. Study Design: Descriptive study with non-probability purposive technique. Setting: Department of Oral & Maxillofacial Surgery Liaquat University hospital Hyderabad. Period: From February 2013 to January 2017. Material & Methods: A total number of fifty pregnant patients were included in the study and preliminary diagnosis of gingival pyogenic granuloma was made clinically. The clinical diagnosis was confirmed by excisional biopsy under local anesthesia (surgical procedure was done following consultation with primary care physician in second trimester or after parturition), and sent for histopathological examination. Removal of dental plaque performed before surgical therapy. Results: Most of the females involve were in age group of 21-30 (68%). Maxillary anterior region was most frequently involved followed by mandibular anterior region. The smallest size of lesion was 1.5mm and largest was 3cm. Conclusion: Pyogenic granuloma in pregnancy occur due to hormonal imbalance, however bacterial dental plaque, calculus and poor oral hygiene are also key factors in development.

Objective: To determine the frequency of carcinoma of Gall Bladder in Hospitalized patients undergoing surgeries for cholelithiasis at tertiary care Hospital. Study Setting: General surgery department of Muhammad Medical College Mirpurkhas. Study Design: Descriptive.  Study Duration: From 2018 to 2019. Methodology: All the patients of cholelithiasis diagnosed via trans-abdominal ultrasound, those who underwent cholecystectomies and either of gender were included. After surgeries, specimens immediately were sent to the Hospital diagnostic laboratory to evaluate the gall bladder carcinoma. The information obtained was noted on a pre-designed proforma. Results: A total 200 patient of gall bladder stone disease were observed who underwent cholecystectomies. Average age was 53.8+5.62 years and male to female ratio was 1:2.5.  Incidence of carcinoma of gall bladder was 4%, which was significantly associated to gall bladder mass, chronic calculus cholecystitis and porcelain gall bladder (p=0.001).  Conclusion: The incidence of the gall bladder cancer in the study population was 4% and its relationship with gall bladder diseases (chronic cholecystitis and porcelain) was found to be significant.

Objectives: To determine the frequency of complications in parotid surgery at tertiary care hospital Hyderabad. Study Design: Cross-sectional study. Setting: Liaquat University, Hyderabad in the Department of General Surgery. Period: August 2016 to December 2017. Methods: We performed retrospective analysis of 43 patients undergoing parotidectomy. All patients undergoing parotidectomy during this time period were followed up for any post-operative complications. Results: A total of 43 patients met or criteria and were reviewed for the study. Amongst them there 31 males and 12 females. 79% of patients had benign parotid tumor while 20.9% had malignant lesion of parotid.  Out of 43 patients, 41.8% (n=18) patients presented with post-operative complications. The most common complication after parotidectomy was facial palsy. Facial palsy was found in 18.6% (n=8) patients. Upon follow-up and treatment, 5 patients improved whereas patients had permanent facial palsy. Conclusion: Most of the lesions of parotid are of benign aetiology, superficial lobe is most commonly involved. Few complications are involved with parotidectomies and facial nerve palsy is the most common complications. With surgical expertise and use of nerve detector, its incidence can be reduced. Other complications of the surgery should be managed at the earliest to prevent damage.

Objectives: To evaluate epidemiological pattern, early diagnostic tool and histological type of parotid gland tumors. Study Design: Prospective cross sectional study. Setting: Department of Oral & Maxillofacial Surgery& General Surgery Liaquat University hospital Hyderabad. Period: From 2013 to 2017. Material & Methods: Study contains 67 patients of parotid tumors after initial diagnosis. These patients were first diagnosed by FNAC (Fine needle aspiration cytology) along with CT scan & MRI where required. Final diagnosis was established after histopathological diagnosis of tumor. Results: Males were predominantly involved in both tumor patterns. Most common age group was 5th decade in both benign and malignant tumors. FNAC has diagnostic sensitivity of almost 90-97%. Out of 67, 51 tumors were benign and 16 were malignant. Pleomorphic adenoma was the most common benign tumor while mucoepidermoid carcinoma was found as most received malignant tumor. Conclusion: Pleomorphic adenoma is most commonly found benign tumor and mucoepidermoid carcinoma is found more in numbers as malignant tumor.