This year Molecular Genetics & Genomic Medicine (MGGM) turns 5 years old. For the editors of this journal it is time for some reflection, "looking back and looking forward". The first issue appeared in May of 2013, 60 years after the publication by Watson and Crick's discovery of the double-helical structure of DNA and 10 years after the completion of the Human Genome Project. The work for this journal began 1 year earlier with the selection of the Founding Editor-in-Chief (EIC) Max Muenke, choice of a journal title, and the Aims and Scope of the journal. Initial options for titles included Human & Medical Genetics, Medical Genetics & Genomic Medicine, and a few others, before Molecular Genetics & Genomic Medicine became the top choice. Suzanne Hart was chosen as Deputy Editor-in-Chief in part because of her expertise that is different from the EIC. Twenty-four colleagues (10 female and 14 male) with a wide range of expertise from 15 different countries were invited to serve on the MGGM Editorial Board. The Aims and Scope of MGGM were and are broad, to encompass a wide range of topics including basic and translational science, technological advances, human and medical genetics, animal models of human disease, pharmacogenomics and translational medicine (Muenke, 2013). From the first Editorial to the Invited Commentaries in each issue, various aspects of genomic medicine have been illustrated: integration of genomic information into the delivery of health care (