The Failure Modes and Effects Analysis (FMEA) method has been widely recognized as a tool that systematically identifies the consequences and failures of the system or process, and reduces or eliminates the chances of the failure. This study applies that method to evaluate the causes of failure in the use of sugarcane machine that have been designed in the previous studies. FMEA approach anticipated the failures at the design stage, so that a more reliable and ergonomic design can be produced for future sugarcane machine. The potential failure identified from the machine consists of capacity issues, machine maintenance, preliminary treatment, and procedures of use. The study found that capacity issues are the priority problems that cause the machine failure. Then, this study proposed some actions to reduce the risk priority number (RPN) on 12 failures.