Vitamins are essential for our daily life. Its shortage in our body can cause many disorders, decreased enzyme activities also affect the genetic factors. Vitamins should be supplied through the diet in the required amount. If it is not supplied properly, vitamin tablets will be prescribed. And also vitamin tablets are the co-medication for therapies such as anticancer, antitubercular, antiviral and anti-HIV treatments. Many newspapers reported that vitamin therapies are causing major health problems like nephro/urolithiasis, it can increase mortality rates in smokers by increasing the risk of lung cancer, it can cause abortion when it is taken during pregnancy. Thus here, we reviewed the adverse effects of vitamin therapy from various reported cases, books, instructions provided from various health organizations and also newspapers, and magazines. It can help health professionals to control and monitor the vitamin therapies and make awareness about the adverse effects and possible side effects of regular vitamin uptake to society.
Background:The contemporary lifestyle has made Cancer as one of the most deadly diseases. Treatment modalities of cancer are many, while chemotherapy seems to be the most common. Though, chemotherapy subsides the disease, it has many side effects in which Chemotherapy induced Nausea and Vomiting (CINV) is frequent. This study aims to evaluate various antiemetics in the prevention of Chemotherapy induced Nausea and Vomiting in cancer patients specifically in Breast, Lung, Cervix and Head & Neck cancers so that the rate of emesis, efficacy and comparative efficacy of different antiemetic combinations in cancer patients can be determined. Methods: A prospective observational study was carried out at a tertiary care hospital in Tamilnadu, South India between January to June, 2015 in which 241 cancer patients receiving antiemetics in their prescriptions meeting our inclusion criteria were analyzed using standard guidelines. A well designed data collection form was prepared to collect the datas. Results: It was observed from our study that the efficacy of different combination of antiemetics, mostly given as triple based regimen, relied on the treatment regimen of the particular cancer, thereby its emetogenic level and NCI-CTC grading score and it was found out that Ramosetron based triple antiemetic regimen was slightly better than Granisetron based regimen to control CINV. Conclusion: It is the need of the h to promote optimal antiemetic medication and ensure that cancer patient receives evidence-based, effective treatments for their health problems.
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