Background. Progress in prenatal diagnosis and prenatal screening in the past 2 decades has facilitated improved diagnostic methods for fetal abnormalities. Objectives. To assess the indications for late termination of pregnancy, gestational ages and to discuss ethical and legal considerations. Methods. A retrospective study compiling and analysing data from justified medical terminations of pregnancies, reported between January 2001 and June 2012 at Charles Nicolle Hospital. Congenital infectious embryofetopathies were excluded. Results. Over this period, there were 77 cases of clinically justified medical terminations of pregnancies-a rate of 1.9 per 1 000 total births. The mean gestational age was 27 weeks. In 33 cases, the medical abortion was performed beyond 26 weeks (42.8%). Fetal malformations were predominantly of the central nervous system. Conclusion. Medical terminations of pregnancy for fetal indications are relatively rare. However, they raise ethical, medical and legal issues, due in part to a late prenatal diagnosis. Such decisions should be taken through a multidisciplinary committee.

We report a rare case of isolated thrombocytopenia related to anti-Ro/SSA antibodies. The mother was followed for unlabeled familial thrombocytopenia. The mother had positive anti-Ro/SSA antibodies. She was asymptomatic without skin lesions or other criteria neither of systemic lupus erythematosus nor other connective tissue disease. Pregnancy was uneventful. The postnatal examination was normal. On the first day of life, blood cells count showed thrombocytopenia at 40 x 109/L. Within the second day of life, platelet level dropped to 20 x 109/L. The management of thrombocytopenia included platelet transfusion and human immunoglobulin infusion. On the fifth day of life, there has been a drop in platelet count to 10 x 109/L requiring renewed platelet transfusion and human immunoglobulin infusion. On the 10th of life platelets rate was stable around 60 x 109/L. The infant had no evidence of cardiac, dermatologic or hepatobilary involvement initially or throughout follow up.

Perinatal-lethal Gaucher disease is very rare and is considered a variant of type 2 Gaucher disease that occurs in the neonatal period. The most distinct features of perinatal-lethal Gaucher disease are non-immune hydrops fetalis. Less common signs of the disease are hepatosplenomegaly, ichthyosis and arthrogryposis. We report a case of Gaucher's disease (type 2) diagnosed in a newborn who presented with Hydrops Fetalis.

Retroperitoneum is a very uncommon site of enteric duplication (ED). We report a new case of retroperitoneal ED cyst suspected in utero. Prenatal ultrasound showed an abdominal cystic mass. Noncommunicating retroperitoneal ED cyst measuring 70 mm × 30 mm was resected. Histopathologic examination confirmed the diagnosis.

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