Litter production which is important for understanding nutrient cycling and assessing productivity in forest ecosystems is poorly studied in the African savannahs, particularly in the savannahs of Cameroon. Thus, litter production and organic compounds of the thirty-six (36) contrasting plant species were studied in the Sudano-guinea savannahs of Ngaoundere, Cameroon. Litter collected in framework of 50 cm x 50 cm under the three tree of each plant species in three sites of the savannahs of Ngaoundere during the period of their maximum fall that from November and January. After two years of collection, mean annual litter production varied from 0.36 in S. longipedunculata to 10.06 t.ha-1.year-1 in F. polita at Dang, from 0.14 in G. aqualla to 9.39 t.ha-1.year-1 in V. paradoxa at Biskewal, and from 0.35 in G. aqualla to 3.64 t.ha-1.year-1 in S. guineense var. macrocarpum at Wakwa. Contribution of leaf litter, fruits and wood were respectively more than 50%, 1.40% and 32% to the total litter. Litter production varied from 2.35 t.ha-1.year-1 at Wakwa to 2.91 t.ha-1.year-1 at Dang, but the sites did not differ significantly among them. Litter cellulose content varied from 4.11 in P. hookeri to 11.84% in V. doniana, that of lignin from 2.28 in V. paradoxa to 8.12% in V. doniana, that of NDF from 21.35 in S. guineense var. guineense to 75.73% in S. guineense var. macrocarpum, and that of phenolic compounds from 0.47 in V. doniana to 16.11% in C. molle. Litter production and organic compounds content were affected by plant diversity, but not by sites in the Sudano-guinea savannahs of Ngaoundere, Cameroon. These results would contribute to well select plant species for their domestication and to management of Adamawa savannahs of Cameroon.