Background: Mild(soft, minimal) protocols have been proposed as an alternative to the classical protocols , a controlled ovarian stimulation is defined as "soft" either when (a) Gonadotrophins (Gn) are given at a lower dose and/or for a short period together with a GnRH-antagonist, or when (b) oral compounds (e.g. anti-estrogens) are used alone or in combination with Gn and GnRH-antagonists. Objectives: The aim of this study was to compare between soft and conventional protocol in ovarian stimulation for poor responders women undergoing Intracytoplasmic sperm injection procedure(ICSI), Patients and methods: This study is A randomized clinical trial, carried out at Assisted Reproduction

Background: A perfect assessment of fetal gestational age is a fundamental procedure in different circumstances including clinical, forensic and archaeological. Objectives: The present study aimed to estimate the value of fetal femur length measurement in gestational age assessment. Patients and methods:The present study is an observational study, conducted on one hundred pregnant women. Their ages ranged from 18 to 34 years admitted to department of Obstetrics and Gynecology, South Valley University Hospitals from August 2020 to August 2021. Results: Femur length (FL) ranged between 1.7cm -6.5cm with a mean value of 4.5±1.2. Biparietal diameter (BPD) ranged between 3.2cm -8.9cm with a mean value of 6.6±1.4. Abdominal circumference (AC) ranged between 11.1cm -31.6cm with a mean value of 22.5±6.0. Fundal level ranged between 17 -36 with a mean value of 26.7±5.4. Agreement coefficient between gestational age by FL and the age of gestation by last menstrual period, BPD, AC and fundal level was (0.992, 0.992, 0.990 and 0.992 respectively) and the correlation was statistically significant. Conclusion:The present work revealed clear associations between the parameters of the femoral growth and the gestational age that demonstrate the significance of these dimensions in the gestational age assessment, and they can be broadly used in forensic circumstances and for investigational functions.

Background: Missed Abortion is non-viable intrauterine pregnancy with either an empty gestational sac or a gestational sac contains an embryo without fetal heart activity. Objectives: The aim of this study was to compare effect of misoprostol with clomiphene citrate, misoprostol with letrozole and misoprostol alone in terminating first trimester missed abortion. Patients and methods: This randomized clinical trial was included patients with missed abortion attending to our outpatient clinic at

Background: Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine and metabolic conditions in premenopausal women. Objectives: The goal of this study was to see the efficacy of Letrozole in conjunction with clomiphene citrate versus Letrozole alone in inducing ovulation in PCOS patients. Patients and methods: This was a randomized clinical trial (RCT) done on a total of 200 patients who came to South Valley University, Obstetrics and Gynecology clinics, after receiving the ethical committee permission and signed informed consent from all participants.Results: Regarding all treatment outcomes, there were no statistically substantial difference among the two groups as regards the following parameters: ovulation, mature follicle number, endometrial thickness, OHSS, single pregnancy, clinical pregnancy, multiple pregnancy and miscarriage, P>0.05. Conclusion: this research showed that in terms of infertility therapy in women with PCOS, the combination of letrozole and CC was linked to"Although there is absolute difference between the two groups in favor of the combined use of letrozole plus clomiphene citrate, this difference is not statistically significant". These new findings indicate that this combined therapy might be a low-risk, low-cost infertility treatments.