Aim: Dermatophytosis is a superficial fungal infection distributed worldwide, more prevalent in the tropical countries like India. Dermatophytosis is diagnosed based on the history, physical examination, and laboratory diagnosis by Microscopic examination of Potassium Hydroxide (KOH) Mount followed by fungal culture. KOH mount is a rapid, simple, time saving and cost effective diagnostic method. The present study was conducted to know the prevalence and common clinical presentations of Dermatophytosis in Hyderabad, South India. Materials and Methods: The study was carried out in Clinical Microbiology section of the Laboratory of the Skin Research Institute in Hyderabad, South India, for a period of 1 year from August 2020 to September 2021. A total of 236 skin scarping samples from clinically suspected cases of dermatophytosis were collected. A detailed clinical history of the patients was recorded and skin scrapping samples was subjected to KOH test. Results: Of all the 236 patients, 186 patients (78.81%) were positive of fungal elements. Males (58.06 %) were more commonly affected than females (41.94%). Tinea corporis was the most common clinical type (50%) followed by Tinea Cruris (22.58%). The microscopic finding revealed 49.46% of samples showing long, septate hyphae, 39.78% of samples showing Spaghetti and meatball appearance and 10.75% of samples showing pseudohyphae with budding yeast cells forms. Conclusions: The prevalence of Dermatophytosis is high in the study population. In experienced hands, a potassium hydroxide mount is one of the most useful procedures in medical mycology and can be used as screening test and routine investigation in the diagnosis of dermatophytosis so that definite treatment can be commenced without delay.

Background: Anemia is widespread public health problem with 1.62 billion people affected globally.  In India, Anemia is considered a major health problem. Children, women of child bearing age and pregnant women are more prone to develop anemia. Anemia affects the physical and mental growth of children, associated with increase maternal and fetal mortality, leads to reduced work productivity in adults. The present study was undertaken to determine prevalence and severity of anemia among patients who attended the outpatient clinics of a Unani research hospital in Telangana.Methods: This hospital based retrospective observational study was conducted from January 2020 to December 2020 to investigate the prevalence, type, and determinants of anemia. The complete haemogram values of all the patients who underwent haemogram investigation were noted, information was compiled, tabulated, and analysed. Descriptive statistics were computed with percentages, mean, standard deviation, and student’s t-test was used find the significance of study parameters.Results: Prevalence of anemia was 26.2% (872/3326), high prevalence of anemia was observed in females (44.04%) compared to males (5.72%) (p<0.0001). The prevalence was more in reproductive age group (58.6%). Moderate anemia (58.6%) was more prevalent followed by mild anemia (36.6%). Microcytic hypochromic blood picture predominates with the incidence of 53.6% followed by normocytic blood picture 42.2%.Conclusions: Results confirmed high prevalence of anemia in females and moderate anemia being more prevalent followed by mild anemia and majority of anemia cases were microcytic, suggesting iron deficiency as the main cause of anemia.

Drugs of traditional system of medicine including Unani and Ayurveda are recommended and used in various diseases since long. These drugs are mainly derived from herbs and plants. Neem is a pre-eminent and a sacred gift of nature. This tree is still regarded as “Wonder tree”, “Nature’s drug store”, “Divine tree”, “Heal all”, “Materia medica”, “Panacea of all diseases” and “Village dispensary” also considered as “An ancient cure for modern world”. In Unani System of Medicine (USM) it is widely used as antiinfective agent in various skin diseases (Amrāḍ-i Jild) such as leprosy, syphilis, tinea, itching and in ulcers. It is very effective in painful menses and dysmenorrhea, chronic joint pain, constipation, intestinal warm (Kirm-i Shikam) and also prefer in the killing of head lices, diabetes and rheumatic arthritis. This study is based on a comprehensive analysis of related articles published in journals using the phrases "Neem or Azadirachta indica ", "Neem research paper", "Neem and Unani Medicine" and "Neem used in traditional medicine" in electronic searches of the PubMed, SCOPUS, Google Scholar advanced search and AYUSH Research Portal. The evidence based scientific and clinical studies reported in the present review confirming the therapeutic efficacy of Azadirachta indica (Neem). Biological active phytoconstituents of Neem also indicate that it may serve as very effective natural medicine in different disease. In this aspect, further in vitro and in vivo studies are needed in respect to explore the recommendations of USM as well as other traditional system of medicines in term of the extensive therapeutic values of Azadirachta indica.

Unani Medicine System is one of the oldest systems with its potent and effective drugs from animal, plant, and mineral sources. Over 2400 years ago, Hippocrates, the founder of medicine, practiced it; however, his medicine includes many ancient Egyptian medications and important components of ancient Mesopotamian customs and traditions. Neurological problems are a significant cause of death, comprising 12% of all deaths globally. Sar' is used for epilepsy in USM, which means falling. Convulsions occur after the patient has fallen due to partial occlusion in the passage of Rūh Nafsānī (psychic pneuma). A vast number of single and multi-ingredient medicines were referenced for epilepsy treatment. Majoon Zabeeb (MZ) is possibly the most presumed polyherbal preparation used in epilepsy. This polyherbal compound has eight components used as a strong anticonvulsant, antispasmodic, antioxidant, deobstruent, memory enhancer, neuroprotective, nervine tonic, and anti-inflammatory agent.

Objectives To analyze the phytochemicals, antioxidant, and anticancer activities on MCF-7 human breast cancer cell line using aqueous, hydro-ethanol, and methanol extracts of different Unani drugs, e.g., Halela Siyah, Aftimoon, Bisfayej, Ustukhudoos, and Kutki. Methods The qualitative examination (alkaloids, terpenoids, tannins, and saponins), anticancer activity, and an antioxidant assay of the three different extracts were done by MTT assay and DPPH assay, respectively, using different Unani drugs. Results The qualitative examination confirmed the substantive presence of phytochemical constituents in all the extracts of these drugs. The Methanolic extract of Halela Siyah had the highest DPPH scavenging activity (91%), while Bisfayej had the lowest (58%). Similarly, the hydro-ethanolic extract showed approximately identical activity for Halela Siyah (89%), Aftimoon (88%), Bisfayej (84%), Kutki (82%), and Ustukhudoos (81%). The aqueous extracts of Halela Siyah (88%) had the highest DPPH scavenging activity, whereas Bisfayej (73%) had the lowest. The methanolic extract of Aftimoon demonstrated the greatest anticancer activity (IC50 – 108), while Aftimoon showed the least activity (IC50 – 316). Halela Siyah (IC50 – 175) and Aftimoon (IC50 – 178) showed substantially the same activity in aqueous extracts. Ustukhudoos hydro-ethanol extracts had the highest (IC50 – 130) activity, whereas Aftimoon had the lowest (IC50 – 204). Conclusions In conclusion, our findings evaluated the presence of phytochemicals, good antioxidant activity, and anticancer activity in different extracts of drugs used in this study. The study shows these drugs have potential anticancer activity against breast cancer in MCF-7 cell lines.