Background: Contrast-induced nephropathy (CIN) is defined as the absolute ≥ 0.5 mg/dL or relative > 25% increase in serum creatinine from baseline on admission to 48–72 h following exposure to intravascular iodinated contrast media. The objective of this research was to assess the predictive value of The PRECISE DAPT score for the development of CIN in acute coronary syndrome cases undergoing PCI and compare its predictive power to the Mehran score. Methods: This Prospective observational research was included 100 cases had Acute coronary syndrome and performed PCI. Cases were classified into group 1 (13 cases had CIN) and group 2 (87 cases had no CIN). Cases were subjected to standard 12-leads ECG, primary PCI and calculation of PRECISE-DAPT, Mehran score scores. Results: PRECISE-DAPT score is a more accurate predictor of CIN than Mehran score (difference between both AUCs 0.183, p =0.005). There was insignificantly different in PCI interventional data and complications between two groups. Conclusions: The PRECISE- DAPT score could be determined easily. This scoring system is effective for estimating CIN at early stage and determining therapy measures. Follow-up of cases had higher PRECISEDAPT score done more carefully and mentioned that these cases have an increased risk of CIN.

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