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‫ــــــ‬ ‫ــــــــــــــــ‬ ‫ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬The goal of this study To assess if high frequency ultrasound correlates with modified Rodnan skin score and inflammatory markers and if it can differentiate between Systemic sclerosis and healthy individuals and if HFU can detect subclinical skin thickening. We recruited 30 consecutive patients with SSc and 40 controls in this case control study. Skin thickness was

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Retinal vasculitis and vein occlusions are common causes of serious visual loss in Behcet’s disease. The aim of the current work was the comparison of the OCTA results of BU cases, BD without uveitis cases &normal control was further subdivided to smokers &non-smokers to permit us to recognize retinal micro-circulation variations at the macular level in BU cases even in the nonattendance of preceding angiographic diagnosing of vasculitis & impact of smoking on BD clinical results of Behcet uveitis(BU), Behcet disease with no uveitis cases &normal control by the following parameters; Vessel density of macular area (VD) & foveal Avascular zone (FAZ) using OCTA. The conclusion of this study shows reduction of vessel density of macular area in Behcet uveitis (BU) rather than Behcet disease without uveitis &normal control & Enlarged FAZ in BU rather than BD without uveitis & normal control. The study results revealed areas of hypoperfusion of macular area even in BD without clinical signifacnce. Hazards of smoking on uveitis cases . There is a need to larger samples & lack of stable treatment protocols.