This study revealed that choroidal thickness measured using SD-OCT increased in women with preeclampsia and healthy pregnant women but the increase in choroidal thickness in preeclampsia was lower than the healthy pregnant controls. This lower rise in choroidal thickness can be generally attributed to the markedly increased systemic vascular vasospasm secondary to preeclampsia.

This study aimed to investigate the macular, retinal nerve fiber layer (RNFL), and choroid thickness alterations using spectral-domain optical coherence tomography in women with polycystic ovary syndrome (PCOS) and to compare them with healthy reproductive-age women volunteers. Study group consisted of 64 patients with PCOS and control group consisted of 60 healthy volunteers. There was a statistically significant difference between PCOS and control groups for choroid thickness (P < .001). Fovea center thickness and temporal inner macula were significantly thinner in the PCOS group than those in the healthy control group (P = .009 and P = .033, respectively). Contrary to these findings, nasal outer macula (NOM) and temporal outer macula (TOM) were statistically thicker in the PCOS group than those in the control group (P = .001 and P < .001, respectively). Increased choroid thickness and RNFL may lead to increase in both retinal volume and retinal thickness in the peripheral side of the retina. Therefore, NOM and TOM region can be accepted sensitive areas in patients with PCOS.

PurposeTo report the therapeutic efficacy and results of an accidentally injected intralenticular sustained-release dexamethasone implant (Ozurdex) in a patient with macular edema secondary to central retinal vein occlusion at 14 months after injection.ObservationsWe present a 70-year-old female patient with central retinal vein occlusion who underwent an Ozurdex injection. Patient discontinued from the treatment period during the 14-month and there was no ophthalmologic examination of the patient. Detailed ophthalmological examination was performed. Ozurdex localization was determined by Pentacam rotating Scheimpflug System. The implant was accidentally injected into the crystalline lens. It did not cause a totally lens opacification but did result only in a posterior subcapsular cataract. The macular edema did not resolve, and the patient underwent phacoemulsification surgery.Conclusions and importanceOzurdex that totally located inside the crystallize lens may not have the therapeutic effects.

BackgroundGestational diabetes mellitus (GDM) is a risk factor for the development of type II diabetes and it causes maternal and child morbidity. Screening for diabetic retinopathy (DR) is important because patients who develop DR have no symptoms until macular edema and/or proliferative diabetic retinopathy (PDR) are already present. The aim of this study was to determine the early retinal findings of GDM.Material/MethodsThis study was conducted in a tertiary research center. We conducted a prospective cross-sectional study with 3 groups: Group 1 consisted of 36 pregnant women with GDM, Group 2 consisted of 24 healthy pregnant women, and Group 3 consisted of 38 healthy non-pregnant women of reproductive age. Spectralis optical coherence tomography (OCT) was used for the assessment. Macular, choroid, and retinal nerve fiber layer (RNFL) thicknesses were evaluated in patients with GDM and comparisons were made among pregnant women with GDM, healthy pregnant women, and healthy non-pregnant women for these parameters.ResultsThe nasal part of the RNFL was significantly thinner in the GDM group than in the healthy pregnant group. None of the patients had retinopathy or macular edema at the time of examination.ConclusionsDecreased nasal part of RNFL thickness may be the first retinal change in patients with GDM. Our study suggests that OCT should be performed for the patients with GDM for detection of early retinal changes associated with GDM.

PEX might weaken choroid circulation by accumulating in choroid vessels. The thinner choroid in the PXG group suggests that ischemia affects the duration of PEX and has a role in the development of glaucoma.