No abstract

Aim: To perform a retrospective evaluation of the morbidity and mortality rates and reliability of venous resection with pancreaticoduodenectomy (PD) procedures in our clinic. Material and Method: The records of 11 patients who underwent PD with venous resection between May 2016 and May 2021 in the Eskişehir Osmangazi University Faculty of Medicine Department of General Surgery were analyzed retrospectively. Results: Eleven patients (five women and six men) were included. The patients’ mean age was 64.09±9.27 years (range 47-78). Four (36.36%) patients underwent type 1 reconstruction, one (9.09%) type 2 reconstruction, five (45.45%) type 3 reconstruction and one (9.09%) type 4 reconstruction. Eight (72.73%) patients experienced venous invasion according to the histopathology reports. Mean time between diagnosis and surgery was 14.91±11.33 days, and the mean follow-up time was 17.64±13.31 months. Grade C pancreatic fistula was observed in one (9.09%) patient, who died on the 17th postoperative day. No patients experienced recurrence or metastasis during surveillance. Conclusion: Pancreaticoduodenectomy with venous resection-reconstruction is safe and the only curative option in patients with pancreatic cancer and venous invasion.

Erkeklerde meme kanseri görülme sıklığı yaklaşık %1'in altında olup oldukça nadirdir. Kadınlardan farklı olarak yaşla birlikte görülme sıklığı artmaktadır. Erkeklerde meme karsinomunun klinikopatolojik özelliklerini, cerrahi ve rekonstrüktif tekniklerini, adjuvan tedavilerini ve klinik sonuçlarını değerlendirmeyi amaçladık GEREÇ VE YÖNTEM: Ocak 2010-ağustos 2020 tarihleri arasında Osmangazi Üniversitesi Genel Cerrahi Kliniğinde ve Yunus Emre Devlet Hastanesi Genel Cerrahi Bölümünde tedavi edilmiş meme kanseri hastaları retrospektif olarak incelendi. BULGULAR: 16 erkek meme kanseri olgusuna rastlandı. Hastaların klinik, patolojik, adjuvan tedavi, nüks ve sağ kalımlarına ait özellikler kayıt edildi. Ortanca yaş 62 idi. En sık prezentasyon şekli sağ memede retroareolar (%62) bölgede ele gelen kitleydi (%68). Hormon reseptör pozitif (%75-95) ve grade 2 (%62) yaygın görülen özellikti. Küratif cerrahi 15 hastaya yapıldı, 1 hasta metastatik olması nedeniyle palyatif tuvalet mastektomi yapıldı. En yaygın cerrahi işlem olarak modifiye radikal mastektomi (MRM) (%88) yapıldı. Bir hastaya muskülokütanöz flep ile rekonstrüksiyon yapıldı. Ortanca takip süresi 53 aydı. Takip süresince 3 hastada (%19) lokal nüks görülürken 6 hasta (%38) kaybedilmiştir. Bunlardan 4 hastanın (%25) kansere bağlı öldüğü kaydedildi. SONUÇ: Erkeklerde meme kanseri nadir görüldüğü, jinekomasti gibi benign hastalıklarla karışabildiği ve erkeklerde meme kanserinin görülmediği algısı yüzünden geç fark edilir. Bu nedenle de tanı konduğunda sıklıkla ileri evrede karşılaşılabilmekte, lokal nüks ve mortalite oranları daha yüksek gözlenmektedir. Bu durum, erkeklerin dikkatini çekmeyi ve bu hastalığın prevalansı ve risk faktörleri konusunda bilinçlenmeyi gerektirir.

Evaluation of lymphatic spread in early stage breast cancer without clinical and radiological evidence of metastasis can be performed by sentinel lymph node biopsy (SLNB). However, controversies about performing the SLNB in patients who have a history of major breast or axillary region surgery keep going. This case report presents the outcomes of a SLNB performed on a 42-year-old woman who had been previously treated with bilateral nipple and skin-sparing mastectomy and breast reconstruction with areolar complex transfer and silicone breast implants. 0.5% diluted methylene blue solution was injected intradermally as a marker. SLNB is an inexpensive and effective method for adequate axillary evaluation in cases with previous mastectomy history. Intradermal injection of 0.5% diluted methylene blue could reduce the risk of skin necrosis and breast prosthesis rupture.

AIM: In this study, we aimed to examine whether the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values of women operated for breast cancer were associated with their clinicopathological features. MATERIAL AND METHOD: The data of 463 females who were operated for breast cancer in our center between Januray 2015 and December 2020 were analyzed retrospectively. Age, menopausal status, hematological values, histopathological features of tumors, presence of hormone receptors, surgical and biopsy techniques were evaluated in detail. NLR and PLR values were calculated using the results of routinely performed hemogram test before the operation, and their relationships with all parameters were analyzed. RESULTS: The ages of the cases ranged from 23 to 88 years, with a mean of 53.57 ± 12.66. Postmenopausal women constituted 62.42% of the cases. A negative correlation was found between age and PLR, but neither PLR nor NLR were found to be associated with menopause status. It was found that high NLR value was associated with high N stage, high TNM stage, high number of metastatic lymph nodes and presence of extracapsular invasion (p