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Opportunistic fungal infections are life-threatening conditions with a high rate of morality, mostly occurring in immunocompromised hosts. We reported the case of mixed mold infection in a 69 year-old patient with latent diabetes mellitus. She was initially admitted for right orbital cellulitis. Cerebro-rhino-orbital mucormycosis and aspergillosis coinfection was diagnosed from mycological testing and histology after nasal biopsy sample. The patient received amphotericin B deoxycholate then voriconazole combined to surgical debridement with a favorable outcome.

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Highlights The prevalence of intestinal amoebiasis is lower in Tunisia compared to other regions in Africa. The clinical diagnosis is challenging due to the absence of specific symptoms. The main treatment of intestinal amoebiasis is metronidoazole for a period of 14 days. The surgical procedure for amoebiasis colitis is only indicated in case of bowel perforation or necrosis.

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