This paper provides a critical evaluation of the Advanced Computing Infrastructure (ACI), which is a fundamental element of the Cyber Infrastructure (CI) 21st of the Century. Whereas the infrastructure focuses widely on the cyber infrastructure required by education, engineering, and science communities to handle more complex issues and problems, the ACI particularly concentrates on ensuring these societies have ready accessibility to the required advanced computing capacities. The CI of the 21st Century and its framework integrate other key complementariness; however, it integrates overlapping elements: scientific instruments, Computational Data-enhanced Engineering & Science (CDE&S), computational science, grand challenge societies, workforce development, Cyber Security (CS), campus bridging, software and data. Various elements were addressed in the CI of the 21st Century in the past decade and processes are in progress to design strategic plans focusing on the different elements.