Under the tide of economic globalization, it is becoming an important choice for enterprises to achieve higher quality development to march toward the international market and increase the depth of internationalization . At present, however, the research on the enterprise internationalization as a whole is not comprehensive and detailed, and visualization tools are not used to reveal the knowledge structure and general characteristics of the field. Based on SSCI, this paper conducts a systematic bibliometric and visual analysis from a multi-dimensional perspective with the help of Bibliometrix, CiteSpace, and VOSViewer, revealing the characteristics, knowledge base and the main hotpots of the field. The literature between 1999 and 2021 was included in the analysis. The results show that: First, from the literature characteristics of enterprise internationalization research, enterprise internationalization has formed a relatively stable core research group and research effort; the research in the field of enterprise internationalization is greatly affected by the level of economic development and international status of the country where the scholars are located. Second, from the perspective of the knowledge base of enterprise internationalization research, the research topics and contents of the highly cited papers provide an fundamental knowledge base. Third, from the main hotspots of enterprise internationalization research, it mainly focuses on the enterprise factors in international trade , family enterprise internationalization issues, and enterprise internationalization related to social and cultural aspects; Socioemotional wealth is an important research frontier.