One of the systems for oil and gas production supports is the nitrogen compression system. Problem found that condition of the compressor has high vibration with the maximum overall the first compressor is 9,813 mm / s RMS, the second compressor is 7,439 mm / s RMS, the third compressor is 7,430 mm / s RMS, the fourth compressor is 13.47 mm / s RMS, the fifth compressor is 13,220 mm / s RMS, and sixth compressor already damaged. This research will discuss the nitrogen compression process in terms of the characteristics of the output fluid flow from the compressor using computational fluid dynamics. The first piping system shows that the standby compressor's flow has a higher pressure reaching 10.72 - 11.82 Pa but it is still acceptable. The second piping system with two compressors in operation shows that the pipeline flows in the opposite direction with high pressure. Flow turbulence occurs, resulting in a higher speed. The highest pressure in the pipeline reaches 44.79 Pa, mostly at the fifth and sixth compressors. The conclusion from this research there is high pressure backflow when one compressor stops and another compressor start running. Prevents direct pressure to the compressor or the condensed fluid from the gas flowing and entering the compressor used valve addition.