BACKGROUND DOT Provider's knowledge, attitudes and perceptions about Tuberculosis play an important role in their ability to care for individuals with Tuberculosis and is a major determinant of successful completion of TB treatment. Objective-To assess Knowledge and Attitude regarding Tuberculosis treatment among DOT Providers of RNTCP registered patients in Kottayam district, Kerala. MATERIALS AND METHODSA cross-sectional study was done among 248 DOT providers of RNTCP registered patients in Kottayam district. DOT Providers were interviewed by the investigator using a structured interview schedule. For assessing knowledge regarding Tuberculosis, a validated questionnaire was used and knowledge score calculated. Data entry and analysis was done using statistical software SPSSv16. RESULTSMean knowledge score out of 15 was 9.19 (SD-4.741). Health staff had a significantly higher knowledge score than Community DOT providers (P<0.001). DOT providers who received training in RNTCP had a significantly greater knowledge score (P<0.001). CONCLUSIONAfter assessing the knowledge and attitude of DOT providers, gaps were found. There is a need to impart training and reorientation courses to update the knowledge of DOT providers regarding the TB disease, its diagnosis, treatment and followup of patients. KEYWORDSKnowledge, Attitude, DOT Providers, Tuberculosis. HOW TO CITE THIS ARTICLE: Sujatha C, Raveendran A, Krishnankutty SL. Knowledge and attitude regarding tuberculosis treatment among DOT providers of RNTCP registered patients in Kottayam district, Kerala. J. Evolution Med. Dent. Sci. 2017;6(90): 6264-6267, DOI: 10.14260/jemds/2017/1362 BACKGROUND Tuberculosis (TB) is a disease that has severely affected communities and nations since times immemorial. It continues to be a leading cause of death even today, despite the availability of effective diagnostic and therapeutic tools. RNTCP has developed National Strategic Plan to be implemented during 2012-2017, the national 12 th Five Year plan period. The Vision is "TB-free India" and Goal is Universal Access to quality TB diagnosis & treatment for all pulmonary & extra pulmonary TB patients including drug resistant and HIV associated TB. The key focus of the programme is to reduce default rates and to prevent the emergence of drug resistance. The key intervention planned is strengthening and improving the quality of basic DOTS services. 1 'Financial or Other Competing Interest': None. Submission 08-10-2017, Peer Review 02-11-2017, Acceptance 09-11-2017, Published 20-11-2017. Corresponding Author: Dr. Chintha Sujatha, Assistant Professor, Department of Community Medicine, Government Medical College, Thiruvananthapuram. E-mail: sujathachintha@gmail.com DOI: 10.14260/jemds/2017/1362 The DOT strategy has been considered one of the most cost-effective health interventions by the World Bank. 2 While DOT is central to the success of tuberculosis control programmes, it is not easy to implement. Several types of providers are carrying out treatment observation in ...