Honey has been used as traditional medicine in many countries and in the world at large before modern medicine was introduced. These substance is not only a waste product produced by honeybees but also a therapeutic agent used as an ant inflammatory, ant fungal, bacterial and ant microbial agent too. This context assess the healing potency of honey on different skin and wound infections such as dermatitis, boils, eczema, burns etc. Many of these complications are eliminated due to the chemical constituents found in honey but these constituents differ more greatly in their distribution across places in Nigeria such places are north, west and eastern parts of Nigeria. These distributions affect the healing potency of many honey collected from these areas. In this context, the sample differ in their potencies and also in their chemical constituents. These areas of collection include Abuja, Nsukka and Ibadan respectively. The honeys obtained are applied on surface wounds and on skin inflammations infected by S. aureus to see whether they differ in their potency or not. Statistical analysis such as Chi-square test (χ2) was applied in order to compare the association between different honeys on skin infected with Staphylococcus aureus. In other aspect of life, honey is used in many candy products and sometimes in substitute for sugars due to its property of flavonoids compounds.

Honey has been used in wound dressing for thousands of years, but only in more recent times has a scientific explanation become available for its effectiveness. The principle aim and objectives of this current work on honey was to confirm this assertion on the usefulness and medicinal value of honey. It also probed the broad-spectrum of antibacterial activity of Honey however we observed that there was much variation in potencies between different honeys from diverse sources. In this context, Gelam, Tualang and Manuka honey is used on wound complication to assess their healing potentials in which each of the honeys are applied on dressing before put on the affected lesions on the skin. Statistical analysis such as chi- square (χ2) test is used to compare association of diverse honey varieties which shows that the differences between honey varieties are not significant (P<0.05). Glucose oxidase is induced but regain its activity if the honey is diluted. It can be concluded from in vitro studies that honey has powerful antimicrobial and anti-inflammatory activities against dermatologically relevant microbes.

The remarkable activity of honey varieties in inflammatory complications is increasingly favorable due to its ability to induce antibodies to produce cytokines in eliminating bacterial infection and other related skin irritations. We investigated this assertion earlier documented in different studies about the potency of honey varieties in four selected hospitals within Nigeria. We also observed in this current work that the potency of honey obtained from different sources varied due to its composition of acids and proteins. Statistical technique, such as ANOVA was used to compare the mean difference of potency of honey in four selected hospitals within Nigeria. The test showed that the mean difference of the potencies of honey in three selected hospitals are not significant (P>0.05). The result of our in-vitro studies showed that honey had powerful antibacterial activities against different species of bacteria. We thus, concluded and suggested that among the countless varieties of honeys produced worldwide, some might have superior antibacterial activities that were yet to be discovered.