To study cervical cytology and cervicovaginal infection in antenatal women.Objectives: To find out by pap smear for inflammatory, atypical squamous cells of undetermined significance (ASCUS), atypical glandular cells of undetermined significance (AGUS) and premalignant lesions in antenatal women.• To find out cervicovaginal infection by wet mount among antenatal women.• Correlation of cervical cytology with cervicovaginal infection.Materials and methods: Five hundred antenatal women, irrespective of gestational age, were enrolled as subjects in this prospective clinical study for blood investigations, wet mount examination of cervical discharge and pap smear.Results: Out of 500 smears, 385 women were having inflammatory smears out of which 301 were having bacterial vaginosis followed by 89 vaginal candidiasis followed by 12 were having trichomoniasis, in which 339 had a preterm delivery. Conclusion:Antenatal visits are a potential opportunity to perform screening by Pap smear and wet mount study to prevent preterm labor and improve perinatal mortality.