The computer machine Artificial Intelligence (Al). Which aims to emulate human intelligence, has become highly active and is introduced into many areas including medicine. The area of Al implementation for better test quality and patient treatment includes stroke medicine. The Stroke is the second leading cause of death, with severe, long term disability. Stroke is a sudden cortical disappearance due to lack of oxygen, narrowing of the blood stream or an inability to provide the consciousness with the pathway. The forms of stroke are ischemic hemorrhagic and acute ischemic. The death risk will continue to rise, according to the World Health Organization, with the next year’s stroke. Various experiments have been undertaken to diagnose stroke disorders. An artificial intelligence is the method for the detection and application deep learning for stroke and its forms.  Keywords: Artificial Intelligence, Machine learning, Stokes, Stroke Prediction, Stroke Disease, Stroke AI technology.

Angioedema may be a rare condition that manifests itself by abrupt localized edema caused by the fluid outflow from blood vessels into surrounding skin and tissue. This case report presents a 54-year old male patient with chronic angioedema (lip) for one year without urticaria. Six months ago, he approached the local clinic and used regular antihistamines by the physician advice. Still, there was no improvement in patient condition. Then he came to the outpatient department of internal medicine of our hospital. Therefore, we have done a series of investigations, in then he diagnosed with Hypothyroidism (TSH 8.05UIu/ml). Then he has prescribed levothyroxine 25mcg. After one month's review, he examined for Anti-thyroid peroxidase antibodies (Anti-TPO). In that examination, those were positive or elevated (mild). According to our research, this may probably be the first autoimmune thyroid disease associated with chronic angioedema without urticaria or hives.

Rhino cerebral orbital mucormycosis is an aggressively spreading fungal infection caused by filamentous fungi of the Mucoraceae family and is found to be more prone in patients with comorbidities that include: uncontrolled diabetes mellitus, immune-suppressed patients, iron and aluminum overload, chronic steroid therapy, severe trauma, and protein-energy malnutrition. A 51year old male patient was admitted to the hospital with a complaint of headache and intermittent fever. The patient had no history of diabetes or denovo hypertension. Based on the analysis of histopathological and radiological investigations, the patient was diagnosed with mucormycosis. The patient furthermore underwent an endoscopic surgical debridement followed by standard treatment including antifungal antibiotic(amphotericin-B) and azole antifungals (posaconazole) along with symptomatic treatment. Though the patient was given all possible therapy available, no improvement was seen in the patient's condition (poor prognosis).