Abstract:Pneumonia is an infection of pulmonary parenchyma, it is an inflammatory cell in alveolar spaces of lungs by infection, and most commonly is by aspiration from oropharyengeal. It can result from variety of causes including infection with bacteria, viruses' fungi, parasites and chemical and physical injury to lungs. CRP is an acute phase protein levels of which rise in response to inflammation. The present study was undertaken with objectives-to study the hs CRP levels in patient of pneumonia and to study CURB 65 and PSI Score in patient of pneumonia. A cross-sectional study was conducted in department of medicine, Muzaffarnagar Medical College, Muzaffarnagar, having100 patients of pneumonia registered at MMC between 1 st April 2014 to 31 st March 2015. CURB 65 and PSI score were calculated for each patient to stratify into their respective risk class hs CRP LEVELS were measured on day 1 and again on day 5 and 7. High admission hsCRP>70 mg /l were effectively predicts poor out come and severe community acquired pneumonia.