No abstract

The uncoordinated hydroxy group of HEDTRA in Cr(hedtra)(H2O) was readily acetylated by acetic anhydride under a mild condition. The coordinated water of the acetylated complex was reversibly substituted by acetate ions at such a great rate as that of Cr(hedtra)(H2O).

Kinetic studies confirm the nucleophilic assistence of the substitutions of the coordinated H2O molecule in (I) by the [Co(NH3)5]3 + moiety bound to one of the CHzCOO" groups of the EDTA4′ ligand.