Using lineage-tracing experiments in mice, we found that a Runx1 enhancer element, eR1, promotes its expression in the isthmus stem cells of stomach corpus as well as pyloric gland in the antrum. We were able to use eR1 to express oncogenic mutations in gastric stem cells, proving a new model for studies of gastric carcinogenesis.

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We propose the one-way jumping finite automaton model, restricting the jumping relation of the recently introduced jumping finite automaton so that the machine can only jump over symbols it cannot process in its current state. The reading head of a one-way jumping finite automaton moves deterministically in one direction within the input word, whereas movement of the reading head of jumping finite automaton is non-deterministic. The class of languages accepted by one-way jumping finite automata is different from that of jumping finite automata, in particular, it includes all regular languages, as opposed to the latter. We study one-way jumping finite automata and obtain closure properties, a pumping lemma, and separation results with respect to the classical language classes of the Chomsky hierarchy.