An adult case of combined hepatocellular-cholangiocarcinoma with variable sarcomatous changes is presented. Histologically, the tumor was composed of hepatocellular carcinoma, cholangiocarcinoma, and sarcomatous portions, including spindle-shaped, pleomorphic, and osteoplastic varieties. There was a transitional cell form between the carcinoma and sarcomatous cells. These tumor elements showed both independent and concurrent metastases. Immunohistochemical examination for keratin revealed positive staining in the tumor cells except for osteoplastic immature cells, whereas vimentin had positive results only in some sarcomatous cells. On the basis of these findings, the possibility of sarcomatous transformation of combined hepatocellular-cholangiocarcinoma was discussed.

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An extremely unique case of a liver tumor occurring in a 70-year-old man is documented in this article. The primary tumor was well encapsulated by a thick, connective capsule and was histologically composed of two distinct elements, i.e., a common hepatocellular carcinoma (HCC) and a rhabdomyosarcoma. Metastasis of HCC was only seen in the left adrenal gland, whereas intrahepatic metastatic foci as well as tumor thrombi occluding the portal vein branches were composed exclusively of rhabdomyosarcoma. The possibility that the rhabdomyoblastic component might have come from the preexisting HCC by way of metaplastic proliferation is discussed. Case ReportA 70-year-old Japanese man was admitted to the Chiba Workmen's Compensation Hospital on February 8, 1986 because of hypertension (1 90/98 mmHg), pretibial pitting edema, and proteinuria (570 mg/dl). He also had loss of appetite, diarrhea, and abdominal pain for several days. There was a 3-year history of diabetes mellitus for which he was not treated, and laboratory data exhibited a high level (1 94 mg/dl) of fasting blood sugar. The value of creatinine clearance was 10 to 20 ml/minute, and a radionuclide renogram revealed a marked decrease in bilateral renal excretion. This oligunc patient was treated for chronic renal failure and diabetes mellitus.From the

A scenario for quantitative prediction of cavitation erosion was proposed. The key value is the impact force/pressure spectrum on a solid surface caused by cavitation bubble collapse. As the first step of prediction, the authors constructed the scenario from an estimation of the cavity generation rate to the prediction of impact force spectrum, including the estimations of collapsing cavity number and impact pressure. The prediction was compared with measurements of impact force spectra on a partially cavitating hydrofoil. A good quantitative agreement was obtained between the prediction and the experiment. However, the present method predicted a larger effect of main flow velocity than that observed. The present scenario is promising as a method of predicting erosion without using a model test.

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