In this paper, a theoretical investigation of negative optoelectronic feedback study in Nano quantum cascade lasers is presented. The present rate equation model has been modified to include the nano laser factors such as the Purcell factor and the spontaneous emission factor. The results indicate that the present rate equation model can be using to study the effect of Purcell factor and the spontaneous emission factor on the negative optoelectronic feedback in Nano quantum cascade lasers. It is found that the increase in Purcell factor value leads to increase in photon number and decrease the carrier number in all quantum states. Also, the dynamic of photon number (S) tends to stable at constant value with the increase of Purcell effect i.e. there is small variation in photon number and carrier number( , , ). The decreases in enhanced spontaneous emission factor value leads to increases in carrier number and decreases the photon number and we note small variation in these values.