No abstract

Polyp size is a biomarker of colon cancer. Manual size measurements are subject to a variety of sources of error. We present an automatic method for segmenting a polyp from a user clicked point. The method is based on front propagation on surface mesh, guided by features that characterize the local protrudedness, its thickness, its resemblance to wall like structures and ridge measures. These measures are designed to characterize growths in the colonic lumen and differentiate polyp growth from other protrusions such as haustral folds. These measures are aggregated and smoothed. Fast marching guided by these features extracts the polyps. Empirical observation suggests that the method successfully segments a variety of polyp shapes in less than 2 s.

In virtual colonoscopy, the clinical need is a smooth centered path from the rectum to the cecum, for interactive navigation along the colonic lumen. The primary challenge is breakages in the colon, due to fecal residue, abnormalities, poor insufflation and inadequate electronic cleansing. Here we propose a method, that is a modification of the classic energy minimized geodesic, that extracts centered paths through fragmented colons. To begin, we perform electronic cleansing, automatically localize 4 points: rectum, cecum, sphlenic and hepatic flexures; followed by region growing and heuristic approaches to generate the initial segmentation. This is followed by a daisy chaining procedure to link possibly large colon blobs that may have been missed as weaker candidate segmentations. We then perform a front propagation to extract a minimal energy path through the ordered set of points. This propagation is guided by multiple forces: (a) A strong force given by the distance to the colon segmentation surface (b) A weak force derived from the CT intensity (c) A weak force from the distance to the surface of weaker candidate colon segmentations (d) A geodesic repulsive force, where the other points exhibit an repelling force in their voronoi partition, the force proportional to the geodesic distance to the point. Our contribution is a path extraction method for the colon that is the energy minimized geodesic (a) favouring centeredness (b) punching through gaps, traversing in so far as possible through lower intensity regions and possibly centered within these gaps (c) ordered through the feature points. Results show improvements of the method over the standard minimal energy path approach.