The coastal zones are highly resourceful and dynamic. In recent times, increased events of tropical cyclones and the devastating impact of the December 2004 tsunami have brought forth the importance of assessing the vulnerability of the coast to hazard-induced flooding and inundation in coastal areas. This study intends to develop coastal vulnerability index (CVI) for the administrative units, known astalukasof the Karnataka state. Seven physical and geologic risk variables characterizing the vulnerability of the coast, including rate of relative sea level change, historical shoreline change, coastal slope, coastal regional elevation, mean tidal range, and significant wave height derived using conventional and remotely sensed data, along with one socioeconomic parameter “population,” were used in the study. A total of 298 km of shoreline are ranked in the study. It was observed that about 68.65 km of the shoreline is under very high vulnerable category and 79.26 km of shoreline is under high vulnerable category. Of the remaining shoreline, 59.14 km and 91.04 km are of moderate and low vulnerable categories, respectively.