The aim of this research was to study the effect of different levels of the extruded full-fat soybean (EFFSB) on growth performance and serum lipids of male turkeys. A trial was carried out using 300 one day male turkey B.U.T (big 6) during 3 feeding periods (starter, grower and finisher, 18 weeks). Poults were selected and divided into four experimental groups with three replicates containing 25 poults each, in a completely randomized design, and were fed experimental diets for 18 weeks. Treatments consisted on: T1 (control, SBM), T2 (10% EFFSB), T3 (15% EFFSB) and T4 (20% EFFSB).There were negligible changes in mortality. The results showed that the level of feed intake was decreased, while feed efficiency and body weight gain was improved in male turkey fed with different levels of the EFFSB. As a result, the best growth performance was determined for male turkeys fed diets containing 15% and 20% of EFFSB, which was exceeded significantly (p<0.05).The experiment confirmed that addition of extruded full-fat soybean in male turkey diets had influenced on serum lipids, so that cholesterol and triglyceride were reduced significantly (p<0.05) on serum lipids of male turkey.