Conjunctival involvement by AIDS-associated Kaposi's sarcoma (KS) is rare, more so in women. We present a case of a 34-year-old African-American woman with AIDS, who was admitted to our hospital and diagnosed with KS of the conjunctiva. To date there are only a few reported cases of AIDS-associated conjunctival KS in the literature. This case is the first case of AIDS-associated conjunctival KS in an African-American woman and emphasizes the importance of considering KS as a differential diagnosis of the conjunctival mass in HIV-positive patients.

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