The medicinal knowledge of herbal plants plays a predominant role in finding new sources of drugs in pharmaceutics. The plant Trichodesma indicum (Linn) R. Br. is a significant constituent of Boraginaceae family with prominent records in conventional folk medicine. The diverse uses of the entire plant parts are being widely studied by in vitro and in vivo experimental methods. The present work is aspired to provide a biological evaluation of the plant that has been explored so far on various parts of the plant such as roots, leaves, and seeds. It also aims to provide a scientific support to the medicinal properties of the various phytoconstituents that are isolated from the plant. Hence, the present review is a comprehensive literature analysis of chemistry, ethanol-pharmacology and the therapeutic uses of T. indicum.
Objective: Geitlerinema splendidum is non-edible blue-green algae available in freshwater systems. It belongs to Pseudanabaenacae genera. In exploring the medicinal properties of algae, our present work aimed to analyze the anti-inflammatory effect of the algae G. Splendidum.Methods: Anti-inflammatory activity was carried out by human red blood cell membrane stabilization assay for ethyl acetate and ethanol crude extracts of alga and found that the ethyl acetate extract has better inhibitory property than ethanol crude extract. Diclofenac was used as the standard drug.
Results:The experimental results obtained are comparable to the reference drug and are found to be dose-dependent. Even at a minimum concentration of 12.5 µg/ml, the percentage inhibition was in the range of 56.6±0.12-58.5±0.03 %, which indicated that the alga G. splendidum has a satisfactory anti-inflammatory activity.
Conclusion:Our present work is supposed to be the first report in exploring the anti-inflammatory effect of the algae G. splendidum.
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