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In addition to the electronic factors, there is a steric factor responsible for the carcinogenicity of polynuclear aromatic hydrocarbons. A carcinogenic polynuclear aromatic hydrocarbon must bear steric resemblance to steroids. One possible implication to this requirement for carcinogenicity is that these hydrocarbons may act on the same sites as steroid hormones.

Procedures for the isolation of pure prodigiosin from Serratia marcescens are described. Prodigiosin occurs in the bacterial strain studied mainly, if not entirely, as an acid derivative. Palmitic acid and an amide, OsiH^-jANi are isolable from the bacterium.The specta of ethyl and isopropyl alcohol solutions of the perchlorate are influenced due to the interaction of the perchlorate with the solvent, which functions as a Lewis base.

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