FIVE FI(tUEE6Among the physiological adjustments to a low barometric pressure an increase in ventilation is perhaps one of the most important. In consequence we may suppose that the native of high altitude possesses a respiratory mechanism adapted for a better ventilation and for an efficient interchange of respiratory gases. But, curiously enough, this logical supposition has not been adequately investigated, and throughout the extensive literature related to high altitude it is only briefly mentioned, or considered as being of secondary importance. This is due to the erroneous idea of interpreting the changes which occur in the organism under the influence of short time exposures to a low oxygen tension as indicating adaptation. It has not been emphasized that, regardless of the time which a man from sea level spends at high altitude, he is always physically, and possibly mentally too, inferior to the native of these high places. Adaptation in its true meaning will be revealed only by studying the man who has been an inhabitant of high altitude for centuries. We have already discussed (Hurtado, '32) the blood morphology of the Indian natives of the Peruvian Andes. The present observations are related to the respiratory adaptation, from the anatomic and anthropomorphic points of view, These investigations have been partly supported by the Medical Faculty of the University of San Marcos (Lima, Peru).
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