Scleromyxedema is an idiopathic cutaneous mucinosis characterized by a papular eruption, skin induration and paraproteinemia. Histologically, fibrolast proliferation can be observed in the upper dermis associated with a mucine deposition. Treatment is difficult and at present there is no totally effective therapeutic modality to control the disease. The present report is on a 68-year-old patient with scleromyxedema without systemic manifestation, who responded to oral steroid therapy.
Os autores descrevem um caso de rosácea granulomatosa em um homem de 39 anos de idade, tratado com a associação de limeciclina oral e metronidazol gel tópico. A rosácea granulomatosa é uma variante da rosácea clássica, rara, caracterizada pela presença de pápulas vermelho-acastanhadas ou pequenos nódulos com base eritematosa e infiltrada, surgindo geralmente na superfície lateral da face e no pescoço. O exame histopatológico evidencia granulomas perifoliculares e perivasculares. A evolução é crônica, e o tratamento inclui antibióticos orais, como a tetraciclina e seus derivados, e medicações tópicas, como metronidazol, ácido retinóico, entre outras.
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