Introduction: Penile enhancement procedures are becoming more common in men looking to achieve a more desirable penile aesthetic. We describe a case of post-procedural dermatitis after receiving penile girth enhancement injections in an adult male and discuss management of penile girth injection side effects. Materials and Methods: We review and present our case alongside a discussion of girth injection complications.Results: Patient's exam and symptoms improved after treatment. Conclusion:Post-procedural complications after penile girth injections seem to be under-reported and unfortunately can result in severe deformity and dysfunction of the penis.