Dandy Walker variant may be asymptomatic and the images found may not indicate them as the cause of developmental disorders, due to its association with multiple syndromes and chromosomal abnormalities. Clinical presentation and prognosis depends on the related disorders, and a multidisciplinary approach is important, because the treatment depends on the symptoms presented.
Purpose To describe the clinical features, histopathological findings, and prognosis of conjunctival Teddy bear granuloma (TBG) diagnosed in a Mexican ophthalmologic referral center in a period of 64 years. Methods We reviewed clinical and histopathological material from all patients with documented conjunctival TBG. Patient′s age, gender, location, clinical signs and symptoms, duration, treatment and, specimen size, were evaluated. Formalin-fixed paraffin embedded 5 microns hematoxylin-eosin stained slides and periodic acid-Schiff special stain as well as examination under polarized light microscopy were performed in all cases. Results A total of 5 conjunctival TBG were collected. The ages of the patients ranged between 2 and 11 with a mean of 6 years. Female to male ratio was 4:1. The right inferior fornix was involved in 4 cases (80%) with clinical diagnosis of conjunctival mass of unknown etiology. Treatment consisted of surgical removal by slit-lamp biomicroscopy (3 cases) and in the operating room (2 cases). No complications were informed in a short follow-up period. Histopathologically, numerous cross-sections of synthetic and non-synthetic fibers surrounded by multinucleated foreign body giant cells, epithelioid histiocytes, lymphocytes, plasma cells and sparse neutrophils were seen. Polarization light microscopy demonstrated numerous birefringent colorful foreign fibers. The follow-up period of the patients ranged between 1 and 32 weeks with a mean of 10 weeks. Conclusions Most patients with TBG are children with vague, non-specific symptoms troubling precise clinical diagnosis. Treatment of choice involves surgical excision of the foreign body granuloma followed by topical corticosteroids. All surgical specimens obtained must be sent for histopathological examination. Special awareness is recommended during COVID-19 pandemic lockdown to prevent potential exposure to fibers that may cause conjunctival TBG.
Purpose: To describe the prevalence and causes of avoidable blindness in people aged 50 and over in the areas of influence of doctors in social service during the years 2018–2019. Methods: This observational, descriptive, cross-sectional study, with analysis of association of variables, was conducted on patients 50 years and older at the national level, selected under simple random sampling, where sociodemographic variables, background, and clinical characteristics were studied. An ophthalmological clinical examination was performed with prior informed consent, and the information was processed and analyzed using Epi Info 7.2 statistical package and SPSS version 25. Results: Overall, 7992 people were evaluated, with a mean age of 62 years; 60.8% (4861) were women and 39.2% (3131) were men. The prevalence of blindness for both eyes was 4.5% (356/7992, 95% CI: 4.1–5.1%, p < 0.001). The prevalence of severe and moderate visual impairment was 1.5% (118/127) and 12.9% (1029)/12.6% (1004) for the right and left eyes, respectively. The main causes of blindness were cataract, refractive error, and glaucoma. Conclusion: The prevalence of avoidable blindness found in the study was higher than expected and the respective causes were consistent with previous studies. Consequently, it is recommended to implement health policies aimed at the prevention and management of avoidable blindness.
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