It is established that very few modern high-quality drugs in the dosage form "Solution for injection" have isoosmotic activity in the range of 280-300 mosmol/l of water. The main part of solutions for injection is hypotonic or hypertonic solutions, which can have osmotic activity in the range of 0 - 4000 mosmol/l of water. The reason for this was that the osmotic activity of drugs is not included in the list of controlled indicators of drugs quality, so it is not subject to control. It is shown that the osmotic activity of drug solutions increases with an increase in the total concentration of all dissolved ingredients present in the solution.  It was found that an excessively high concentration of the drug in the solution gives it an excessively large hyperosmotic activity, which can cause a local irritant and cauterizing effect at the injection sites due to dehydration of the cells. Therefore, to exclude post-injection abscesses, it is proposed to dilute the hypertonic drug with water for injection until it is given isotonic activity.

Abstract. In the laboratory studied the dynamics of rheology of water solutions with plasmainflammatory and antiseptic funds when mixing them with blood, plasma and pus under the influence of the following physical and chemical factors of local interaction: gravity, specific gravity, temperature, relative viscosity, internal pressure, sparkling water, total concentration of the ingredients, surface activity, volume of acid and osmotic activity of medicines. Found that the rheology of biological liquids improve hyperthermic, highly alkaline and highly carbonated solution medicines. For the dilution of pus, dense festering mass of sulfur plugs and tear stones invited to apply heated to +39 -+42°C with aqueous solution of 0.5 -3% hydrogen peroxide and 0.5 -10% sodium bicarbonate saturated with carbon dioxide to excess pressure 0.2 ATM. IntroductionCurrently in medicine and veterinary medicine are very widely used antiseptic and substitutes plasma, which shall be entered accordingly in the festering wounds (cavity) and in the blood [1]. Traditionally, nobody examines the processes of diffusion of solutions in these biological fluids, believing that these funds are equally bred blood and pus. The medicines of these groups are used in the form of water solutions entered in very large quantities (amounts), calculated in hundreds of milliliters. And still the essence of conventional technologies the use of these drugs, namely the essence of intravenous and intracavitary injections, is to introduce into the blood and pus cold substitutes plasma, antiseptic and even disinfectants solutions [2][3][4][5][6]. Such technology application drugs is so routine that its efficiency is not in doubt, processes of diffusion of drug in the blood and pus not investigated and no new technologies radically increase the efficiency of cultivation of blood (plasma) and dense festering mass [5,7,8]. At the same time, us has received a large amount of scientific evidence proving the existence of significant shortcomings of traditional technologies of drug cultivation of blood and pus, explaining the nature of the deficiencies identified and showing the way of effective modernization of conventional breeding techniques of blood and pus using famous plasma-inflammatory and antiseptic funds [9][10][11][12][13][14][15]. Our results show that to achieve a powerful clinical success (for the rapid and radical dissolution of blood clots, remove blood clots, dense purulent masses, ear wax and others) it is enough only to optimize processes rheology of drugs and dense and viscous colloidal fluids [16][17][18][19][20][21].

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